James Dahlman

James Dahlman is a bioengineer whose lab works at the interface of chemical engineering, genomics, and gene editing by applying big data approaches to nanomedicine. His lab pioneered DNA barcoded nanoparticles to measure how hundreds of nanoparticles deliver mRNA and siRNA in vivo.

• Barcoded nanoparticles for high throughput in vivo discovery of targeted therapeutics (2017) Paper
• Testing thousands of nanoparticles in vivo using DNA barcodes (2019) Paper
• Nanoparticle single-cell multiomic readouts reveal that cell heterogeneity influences lipid nanoparticle-mediated messenger RNA delivery (2022) Paper
• Piperazine-derived lipid nanoparticles deliver mRNA to immune cells in vivo (2022) Paper