Pannucci's educational background encompasses Fine Arts with printmaking as a major focus and art history as a secondary area of study. Her professional artistic practice has spanned printmaking, textiles, mixed-media, photography, and interactive sculpture. Her exhibitions have been displayed at prominent institutions including The American Craft and Cooper-Hewitt museums in New York City. She has received commissions from Citicorp, The Discovery Museum in Bridgeport CT, The Staten Island Children's Museum, and the NYC Metropolitan Transit Authority. In 1988, she established Art & Science Collaborations, Inc., developing pioneering art-science programming including symposia, public panels, exhibitions, and projects that revitalized the "art & technology" movement throughout the 1990s. ASCI organized four international ArtSci Symposia between 1998-2002, after which the organization shifted focus to "art-science." Since 2006, ASCI has conducted annual international competition exhibitions at the New York Hall of Science, featuring science-inspired themes and co-judged by art and science experts. Event partners have included The American Museum of Natural History, the Graduate Center of CUNY, Liberty Science Center, New York Hall of Science, and The Cooper Union for the Advancement of Science and Art.